Bone: An Outstanding Composite Material

InterLynk scientists from INEGI & the University of Aveiro participated to study bone structure, its properties, and behavior to better understand how to construct artificial biomimetic composites that allow for improved bone repair and regeneration. The InterLynk project builds on such knowledge, developing multi-material 3D scaffolds with exceptional biofunctionality, mimicking the bone’s natural nanocomposite architecture and those of the interconnecting tissues and transitional zones among them. They presented their results in a recent review article entitled “Bone: An Outstanding Composite Material” and published in Applied Sciences.

InterLynk scientists and contributing authors: Natacha Rosa, Susana Olhero, Ana Rita Reis, Marco Parente

Further authors: Marcelo F.S.F. Moura, Ricardo Simoes, Fernao D. Magalhães, Antonio Torres Marques, João P. S. Ferreira, Mariana Carvalho

Applied Sciences, March 2022

https://doi.org/10.3390/app12073381

Bone: An Outstanding Composite Material

Abstract:

Bone is an outstanding, well-designed composite. It is constituted by a multi-level structure wherein its properties and behavior are dependent on its composition and structural organization at different length scales. The combination of unique mechanical properties with adaptive and self-healing abilities makes bone an innovative model for the future design of synthetic biomimetic composites with improved performance in bone repair and regeneration. However, the relation between structure and properties in bone is very complex. In this review article, we intend to describe the hierarchical organization of bone on progressively greater scales and present the basic concepts that are fundamental to understanding the arrangement-based mechanical properties at each length scale and their influence on bone’s overall structural behavior. The need for a better understanding of bone’s intricate composite structure is also highlighted.

Please read on to find out more.

Learn more about INEGI’s and the University of Aveiro’s role in InterLynk.

 

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