Biomaterials of human source for 3D printing strategies

InterLynk scientists from the University of Aveiro’s CICECO Institute, including Master’s student João Rocha Maia reviewed the state of the art on “Biomaterials of human source for 3D printing strategies” and published their findings in The Journal of Physics: Materials. This is valuable knowledge for our InterLynk scientists who use human-derived materials to build highly bioactive and biocompatible scaffolds to treat damaged or diseased multi-tissue biosystems. They combine different materials with human blood-derived platelet lysates as a common matrix for bioinks which in turn will be used in additive manufacturing to produce the final InterLynk scaffolds. 

InterLynk contributors from the University of Aveiro: João Rocha Maia, Rita Sobreiro-Almeida, João F. Mano

Contributor from the University of Lorraine: Franck Cleymand

Journal of Physics: Materials, Jan. 2023

https://doi.org/10.1088/2515-7639/acada1

Biomaterials of human source for 3D printing strategies

Abstract

Three-dimensional printing has risen in recent years as a promising approach that fast-tracked the biofabrication of tissue engineering constructs that most resemble utopian tissue/organ replacements for precision medicine. Additionally, by using human-sourced biomaterials engineered towards optimal rheological proprieties of extrudable inks, the best possible scaffolds can be created. These can encompass native structure and function with a low risk of rejection, enhancing overall clinical outcomes; and even be further optimized by engaging in information[1]and computer-driven design workflows. This paper provides an overview of the current efforts in achieving ink’s necessary rheological and print performance proprieties towards biofabrication from human-derived biomaterials. The most notable step for arranging such characteristics to make biomaterials inks are the employed crosslinking strategies, for which examples are discussed. Lastly, this paper illuminates the state-of-the-art of the most recent literature on already used human-sourced inks; with a final emphasis on future perspectives on the field.

Click here to read the entire article.

Learn more about the University of Aveiro’s role in InterLynk.

CONTENT WILL BE LOADED HERE
LEFT CONTENT WILL BE LOADED HERE
RIGHT CONTENT WILL BE LOADED HERE