Developing solutions for tissue regeneration

An unprecedented biomaterial and fabrication platform to achieve a breakthrough in 3D bioprinting technologies and provide innovative scaffolds for damaged or diseased multi-tissue biosystem repair

This is InterLynk

InterLynk

strength

Human-based, patient-specific, multimaterial 3D scaffolds

The repair of biological architectures where multiple tissues, as bone, cartilage, ligament and tendon, are arranged together and interact to produce function, is a complex process requiring differential biochemical and mechanical cues. InterLynk partners will develop multimaterial 3D scaffolds with exceptional biofunctionality to induce tissue-specific regeneration of such anatomical structures.

Structural complexity

Multiple materials will be combined in a same scaffold and a portfolio of scaffolds will be developed to mimic the complexity of the microenvironment of multi-tissue biosystems.

Innovative fabrication

New technological solutions for additive manufacturing (AM) will be developed for a fine control of biomaterial spatial organization and distribution during scaffold fabrication.

Bioactivity and biocompatibility

InterLynk scaffolds will be highly bioactive and biocompatible thanks to the combination of different materials with human blood-derived platelet lysates as a common matrix component with cell-recruiting and pro-regenerative capacity.

Customized design

The development of computational modeling tools and the use of medical imaging data will allow to develop personalized medicine approaches to multi-tissue regeneration.

InterLynk

WORK

PLAN

The ambition of the InterLynk Project is to radically transform the design and fabrication of scaffolds for multi-tissue regeneration, and demonstrate the potential of the new regenerative solution in the total replacement of the dissimilar, weight-bearing tissues composing the temporomandibular joint.

Development of a portfolio of biomaterials

Multimaterial additive co-processing

Validation

Strategies for health technology co-creation

InterLynk

Consortium

8 partners including universities, a research&technology organization and SMEs, from 4 EU countries

A transdisciplinary team with expertise in materials science, AM systems, manufacturing process modelling, computational biomechanics, tissue engineering, biology and regenerative medicine, will collaborate to expand the frontiers of bioprinting, personalized and regenerative medicine.

METATISSUE Portugal Promoscience Italy UAVR Portugal EVT Germany C-UMB Germany Kuros Netherlands INEGI Portugal MU Netherlands InterLynk
UAVR METATISSUE INEGI EVT MU C-UMB Kuros Promoscience

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Updates on InterLynk achievements and initiatives

Project

CONTACTS

João Mano Project coordinator
General enquiries
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